Protein Details: Voltage-gated hydrogen channel 1

Protein ID

ICDB_Pro_1397

Protein Name

Voltage-gated hydrogen channel 1

Gene Name

HVCN1; VSOP; UNQ578/PRO1140

Organism

Homo sapiens (Human)

Length

273 amino acids

AlphaFoldDB

AF-Q96D96-F1-model_v4.pdb

Function

Sequence

MATWDEKAVTRRAKVAPAERMSKFLRHFTVVGDDYHAWNINYKKWENEEEEEEEEQPPPTPVSGEEGRAAAPDVAPAPGPAPRAPLDFRGMLRKLFSSHRFQVIIICLVVLDALLVLAELILDLKIIQPDKNNYAAMVFHYMSITILVFFMMEIIFKLFVFRLEFFHHKFEILDAVVVVVSFILDIVLLFQEHQFEALGLLILLRLWRVARIINGIIISVKTRSERQLLRLKQMNVQLAAKIQHLEFSCSEKEQEIERLNKLLRQHGLLGEVN

PDB Structures

3A2A 5OQK

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Epilepsy;Early-Onset;4;Vitamin B6-Dependent

Location

phagocytes; Breast tumor tissue

DOI ID

10.1038/nature04569; 10.1101/gr.2596504; 10.1038/nature04700

RefSeq

NP_001035196.1 [Q96D96-1]; NP_001243342.1 [Q96D96-4]; NP_115745.2 [Q96D96-1]; XP_005254005.1 [Q96D96-1]; XP_011537147.1 [Q96D96-1]; XP_011537148.1 [Q96D96-1]; XP_011537149.1 [Q96D96-1]; XP_016875516.1 [Q96D96-1];